Lifetime clinical presentation of Still's disease in the Afro-descendant population of the French West Indies.

Introduction: The continuum in Still's disease has never been addressed in Afro-descendant (AD) populations. The aim of this study was to compare the features of Still's disease between children and adults in the AD population of French West Indies (FWI).

Methods: Retrospective longitudinal study from January 2000-2022.

Orange luminescence of α-AlO related to clusters consisting of F centers and divalent cations.

The orange luminescence of α-AlO under UV excitation is characterized by a 2.07-eV orange broadband emission that has not yet been elucidated. This emission is present in natural and synthetic crystals and powders, as well as in Be-treated samples.

Personalized Cancer Vaccines Directed against Tumor Mutations: Building Evidence from Mice to Humans.

Personalized vaccines directed to tumor mutations have recently gained significant momentum. On the basis of the concept of stimulating T-cell responses against neoantigens encoded by a tumor's host of personal mutations, these vaccines utilize genome or exome sequencing, mutation calling, and epitope prediction followed by manufacturing of a customized vaccine for each patient. In their 2012 Cancer Research publication, Castle and colleagues provided evidence that vaccinating with long peptide vaccines encompassing neoantigens can generate robust immune responses and induce antitumor activity in a mouse B16F10 melanoma.

Luminescence Properties of AlO:Ti in the Blue and Red Regions: A Combined Theoretical and Experimental Study.

Using jointly experimental results and first-principles calculations, we unambiguously assign the underlying mechanisms behind two commonly observed luminescence bands for the AlO material. Indeed, we show that the red band is associated with a Ti - transition as expected, while the blue band is the combination of the Ti + O → Ti + O and V+ → V de-excitation processes. Thanks to our recent developments, which take into account the vibrational contributions to the electronic transitions in solids, we were able to simulate the luminescence spectra for the different signatures.