Publications by authors named "E W Craig"
Benzo[]pyrene and phenanthrene hemoglobin adducts as biomarkers of longer-term air pollution exposure.
Environ Sci Process Impacts
November 2024
Article Synopsis
- The study examines PAH-hemoglobin adducts in blood samples from pregnant women in Rochester, NY, as potential long-term exposure biomarkers for air pollution.
- Researchers measured specific hydrolysis products of PAH-hemoglobin adducts (BaPT and PHET) and linked these to cumulative exposure to particulate matter (PM) during pregnancy.
- The results indicated positive correlations between these biomarker levels and PM exposure over specified gestational weeks, highlighting PAH-hemoglobin adducts as effective indicators of longer-term air pollution exposure, while no link was found with NO exposure.
Psoriatic arthritis phenotype clusters and their association with treatment response: a real-world longitudinal cohort study from the psoriatic arthritis research consortium.
Ann Rheum Dis
November 2024
Objectives: To identify phenotype clusters and their trajectories in psoriatic arthritis (PsA) and examine the association of the clusters with treatment response in a real-world setting.
Methods: In the multicentre PsA Research Consortium (PARC) study, we applied factor analysis of mixed data to reduce dimensionality and collinearity, followed by hierarchical clustering on principal components. We then evaluated the transition of PsA clusters and their response to new immunomodulatory therapy and tumour necrosis factor inhibitor (TNFi).
Background/objectives: S-adenosylmethionine (SAMe) is a natural compound implicated in the treatment of liver dysfunction. In this systematic review, our objective was to determine the efficacy, safety, and optimal dose of SAMe in liver diseases.
Methods: Using the PRISMA methodology, we searched PubMed, CINAHL, and Web of Science using key MeSH search terms.
A simple active fluid model unites cytokinesis, cell crawling, and axonal outgrowth.
Front Cell Dev Biol
October 2024
While the structural organization and molecular biology of neurons are well characterized, the physical process of axonal elongation remains elusive. The classic view posited elongation occurs through the deposition of cytoskeletal elements in the growth cone at the tip of a stationary array of microtubules. Yet, recent studies reveal axonal microtubules and docked organelles flow forward in bulk in the elongating axons of , chick sensory, rat hippocampal, and neurons.
View Article and Find Full Text PDFInvasive meningococcal disease (IMD) is a severe illness that can have devastating effects; outbreaks are uncommon in the United States. Vaccination is the preferred control measure for IMD outbreaks when a defined population at risk (e.g.
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