Publications by authors named "E Vuhahula"
Background: Malignant salivary gland tumors (SGTs) present diagnostic challenges and limited treatment options. This study aims to determine the proportion of malignant SGTs overexpressing the androgen receptor (AR) by immunohistochemistry (IHC) and its association to age, sex, anatomical site, histopathological subtype and grade which may inform customized treatment approaches.
Methodology: This was a retrospective cross-sectional analytical study of archived paraffin embedded tissue blocks of malignant SGTs diagnosed at MNH Central Pathology Laboratory (CPL) from January 2019 to December 2022.
Article Synopsis
- A study was conducted to evaluate the STRAT4 Assay's effectiveness using fine-needle aspiration biopsy (FNAB) samples for breast cancer testing in Tanzania, aiming to improve biomarker accessibility in low-resource settings.
- The research involved collecting FNAB specimens from patients with palpable breast masses, using various testing protocols and excluding those with previous breast cancer diagnoses or specific conditions like pregnancy.
- The analysis compared STRAT4's performance against established testing methods based on factors like concordance, sensitivity, specificity, and diagnostic accuracy over a three-year period involving 208 patients.
High-risk human papillomavirus genotyping in cervical cancers in Tanzania.
Infect Agent Cancer
August 2024
Background: High-risk human papillomavirus (hrHPV) infection causes almost all cervical cancer. Women living with human immunodeficiency virus (Women living with HIV: WLWHIV) are at a six-fold increased risk of developing cervical cancer. This study assessed hrHPV types in cervical cancer by HIV status and histologic subtypes at Muhimbili National Hospital (MNH) in Tanzania.
View Article and Find Full Text PDFContext.—: Rapid onsite evaluation (ROSE) is critical in determining sample adequacy and triaging cytology samples. Although fine-needle aspiration biopsy (FNAB) is the primary method of initial tissue sampling in Tanzania, ROSE is not practiced.
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