Publications by authors named "E Vrijlandt"

Objective: To characterize different phenotypes of early pulmonary hypertension (PH) in preterm infants and their respective associations with bronchopulmonary dysplasia (BPD) and survival.

Study Design: A prospective cohort study in a tertiary university medical center from June 2016 until March 2019. Infants with a gestational age <30 weeks and/or a birth weight <1000 g were included.

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Article Synopsis
  • Moderate-late preterm (MLP) births, occurring between 32 and 37 weeks of gestation, are associated with lower expiratory airflow well into later life compared to term-born individuals.
  • A systematic review identified 15 studies that showed participants born MLP had significantly lower z-scores in various spirometric measures (like FEV and FVC) when compared to term-born controls and expected norms.
  • The findings suggest that while the reductions in airflow are modest, clinicians should monitor individuals born MLP for potential respiratory issues, as they may be at a higher risk.
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Introduction: Supplemental oxygen is the most important treatment for preterm born infants with established bronchopulmonary dysplasia (BPD). However, it is unknown what oxygen saturation levels are optimal to improve outcomes in infants with established BPD from 36 weeks postmenstrual age (PMA) onwards. The aim of this study is to compare the use of a higher oxygen saturation limit (≥95%) to a lower oxygen saturation limit (≥90%) after 36 weeks PMA in infants diagnosed with moderate or severe BPD.

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The etiology of nonimmune hydrops fetalis is extensive and includes genetic disorders. We describe a term-born female neonate with late onset extensive nonimmune hydrops, that is, polyhydramnios, edema, and congenital bilateral chylothorax. This newborn was successfully treated with repetitive thoracocentesis, total parenteral feeding, octreotide intravenously and finally surgical pleurodesis and corticosteroids.

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