Publications by authors named "E Vinatier"
Article Synopsis
- Pseudoxanthoma elasticum (PXE) is a rare genetic disorder that leads to abnormal calcium deposits in elastic tissue, causing skin changes and other health issues.
- The study focused on a 13-year-old patient with flare-ups in PXE lesions, leading to a closer examination of the inflammation involved through skin biopsies and various analyses.
- Findings showed inflammation with T-cell infiltrates in the skin, particularly with a Th1 response, suggesting an inflammatory role in PXE disease, but the exact impact on the condition needs more research.
Article Synopsis
- Pernicious anemia (PA) causes difficulty in absorbing vitamin B12 due to a lack of intrinsic factor, leading to the standard treatment of intramuscular injections, though oral supplementation has potential.
- This study evaluated the effectiveness of oral vitamin B12 supplementation on patients diagnosed with PA by measuring various plasma and urinary vitamin B12-related biomarkers over one year.
- Results revealed that after one month of oral supplementation, 88.5% of participants were no longer deficient in vitamin B12, with significant and sustained improvements in relevant biomarkers throughout the study, indicating oral supplementation may be a viable treatment option.
Background & Aims: While vitamin B12 (B12) deficiency is considered as the hallmark of pernicious anemia (PA), iron deficiency (ID) is also prevalent. Indeed, this auto immune gastritis is responsible for parietal cell atrophy and increase in gastric pH, leading to impaired iron absorption. We compared PA patients' features according to their iron status at PA diagnosis, and we assessed the iron status recovery after oral or intravenous iron supplementation.
View Article and Find Full Text PDFA predictive mortality score in ANCA-associated renal vasculitis.
Nephrol Dial Transplant
August 2024
Background: Several scores have been developed to predict mortality at anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) diagnosis. Their prognostic value in Caucasian patients with kidney involvement (AAV-GN) remains uncertain as none has been developed in this specific population. We aimed to propose a novel and more accurate score specific for them.
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