[Acute renal insufficiency in a patient with intra- and extracapillary Henoch's nephritis].

Case is described with acute renal failure in Henoch's nephritis with intra- and extracapillary cellular proliferation. The disease was manifested with its classical picture: characteristic purpura, articular pains in the wrist and ankle joints, mucous-bloody diarrhea. The renal changes originated at the very beginning of the hemorrhagic vasculitis and clinically was manifested with acute renal failure and severe nephrotic syndrome.

Antiviral activity of tetrahydro-2(1H)-pyrimidinones and related compounds.

24 derivatives of tetrahydro-2(1H)-pyrimidinone and related compounds were tested in vitro for antiviral activity against representatives of six viral taxonomic groups. The screening was carried out by a two-stage procedure including the agar-diffusion plaque-inhibition test and the one-step growth cycle setup. A distinct activity of three mono- and bis-morpholinomethyl derivatives of tetrahydro-2(1H)-pyrimidinone (THP), 1,3-bis(piperidinomethyl)-THP, the 1-morpholinomethyl derivative of tetrahydro-2(1H)-pyrimidinethione (THPT) and the related N,N'-bis(morpholinomethyl)-urea against the fowl plague virus was established.