Publications by authors named "E Vasbinder"
Adherence to single inhaler triple therapy and digital inhalers in Chronic Obstructive Pulmonary Disease: a literature review and protocol for a randomized controlled trial (TRICOLON study).
BMC Pulm Med
July 2024
Article Synopsis
- Medication non-adherence in COPD patients is a pressing issue, prompting interest in simpler treatment options like single-inhaler triple therapy (SITT) over multi-inhaler triple therapy (MITT) and the use of smart inhalers.
- A literature review examining adherence levels between SITT and MITT found that most observational trials favored SITT for better adherence and clinical outcomes, while smart inhalers generally showed a positive but varied impact.
- The TRICOLON trial is a planned study to further investigate the effectiveness of SITT and smart inhalers on improving adherence among COPD patients, involving 300 participants across ten hospitals.
Article Synopsis
- Adalimumab has become a more affordable option for treating inflammatory bowel disease (IBD) since its patent expiration, but adhering to the medication is crucial for its effectiveness.
- This study analyzed the relationship between high refill-adherence (defined as medication possession ratio of 80% or more) and disease activity in IBD patients using a retrospective approach.
- Results showed that patients with high adherence had significantly lower rates of active disease, emphasizing the importance of sticking to adalimumab therapy for better health outcomes and potentially reducing the need for costlier alternatives.*
The attainment of target hemoglobin levels in hemodialysis patients is low. Several factors play a role, such as hyporesponsiveness to erythropoiesis-stimulating agents (ESA), but also suboptimal prescribing of ESA and iron. The goal of this study was to investigate if a pharmacist-managed dosing algorithm for darbepoetin alfa (DA) and iron sucrose improves the attainment of target hemoglobin levels.
View Article and Find Full Text PDFObjective: To study the association of workarounds with medication administration errors using barcode-assisted medication administration (BCMA), and to determine the frequency and types of workarounds and medication administration errors.
Materials And Methods: A prospective observational study in Dutch hospitals using BCMA to administer medication. Direct observation was used to collect data.
Real-time medication monitoring (RTMM) is a promising tool for improving adherence to inhaled corticosteroids (ICS), but has not been sufficiently tested in children with asthma. We aimed to study the effects of RTMM with short message service (SMS) reminders on adherence to ICS, asthma control, asthma-specific quality of life and asthma exacerbation rate; and to study the associated cost-effectiveness.In a multicentre, randomised controlled trial, children (aged 4-11 years) using ICS were recruited from five outpatient clinics and were given an RTMM device for 12 months.
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