Meningiomas are the most common benign intracranial neoplasms. Nearly 20% of all primary intracranial tumors are meningiomas. Primary intraosseous meningiomas are a subtype of the meningiomas that represents the most uncommon manifestation of meningiomas.
View Article and Find Full Text PDFThe lesion detection capability and clinical effectiveness of dual-head coincidence gamma camera imaging (c-PET) were compared with those of dedicated positron emission tomography (d-PET) in 37 cancer patients who underwent whole-body c-PET and d-PET imaging after administration of 370 - 540 MBq (18)F-fluorodeoxyglucose. Eighty-nine lesions were detected on c-PET whereas 133 lesions were seen with d-PET imaging. The relative sensitivity of c-PET compared with d-PET was 62% and 73% for lesions < 15 and > or = 15 mm, respectively, and the relative concordance rate was 84% when the patients were restaged.
View Article and Find Full Text PDFUnlabelled: 99mTc-d,1-hexamethylpropyleneamine oxime (HMPAO) is widely used as a labeling agent for leukocytes in the diagnosis of inflammatory or infectious foci. Cytotoxicity studies have indicated that intracellular labeling of leukocytes with (111)In compounds may have severe detrimental effects on the cells.
Methods: In this study, the radiotoxic effects on mixed lymphocytes after labeling with (99m)Tc-HMPAO was investigated using the cytokinesis-blocked micronucleus assay and chromosomal aberration assay.