Publications by authors named "E Van Campo"
Purpose: Hematological toxicities (HTs) in lung cancer (LCa) may compromise the delivery of Radio-Chemotherapy (RTCT), and consequently affect the control of the disease. The aim of this study is to evaluate the association of Single nucleotide polymorphisms (SNPs) with HT.
Material/methods: In this prospective multicentre study, 264 patients with primary LCa treated with RTCT between 2012 and 2018 were included.
Previous studies have reported that chronic lymphocytic leukemia (CLL) shows a de novo chromatin activation pattern as compared to normal B cells. Here, we explored whether the level of chromatin activation is related to the clinical behavior of CLL. We identified that in some regulatory regions, increased de novo chromatin activation is linked to clinical progression whereas, in other regions, it is associated with an indolent course.
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- Aggressive B-cell lymphomas are diverse tumors linked to various B-cell development stages, with this review highlighting recent advancements in their diagnosis.
- The article examines the characteristics of different subtypes, including diffuse large B-cell lymphoma and Burkitt lymphoma, focusing on how to distinguish them.
- It emphasizes the need for a standardized method that combines morphological, immunophenotypic, and genetic information to improve diagnostic accuracy and patient outcomes.
The presence of a monoclonal protein detected by serum immunofixation electrophoresis (sIFE) has been reported as an adverse prognostic factor in chronic lymphocytic leukemia (CLL). However, the genetic underpinning of this finding has not been studied. We retrospectively studied 97 CLL patients with simultaneous information on sIFE and genetic alterations detected by next-generation sequencing.
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