[Absorption spectrum of admixtures coloring butyl acetate extract].

Colour of butyl acetate extract (BAE) at the clarification stage in chemical purification of benzylpenicillin is one of the important qualitative parameters necessary for the process control. BAE is benzylpenicillin-enriched butyl acetate with colouring pigments and admixtures of unknown nature. The routine laboratory photocolorimetric method provides only periodical control.

[Photometric control of the presence of potassium benzylpenicillin crystals after centrifugation].

A photometric (turbidimetric) method was proposed for automatic control of the content of potassium benzylpenicillin crystals after centrifugation. The optical properties of the technological media were studied. It was found that along with intensive absorption in the UV spectrum due to the presence of the penicillin and its degradation products the solutions absorbed the light of the visible spectrum (400-700 nm).