Pharmaceutical Composition for Improving Physical Working Capacity.

For development of a pharmaceutical composition improving physical performance, effects of various drugs and their combinations on forced swimming test performance were studied on laboratory rats. Maximum increase in animal performance was produced by a 3-component composition asparcam+mildronate+metaprote in proportion of 5.0, 10.

[Malignant lymphomas of the skin (clinico-morphological parallels)].

On the basis of clinico-morphological analysis of 104 patients with malignant skin lymphomas (MSL) they are subdivided into two groups: epidermotropic (mycosis fungoides, prolymphocytic and lymphoblastic MSL with sinuous nuclei, histiocytic MSL) and non-epidermotropic (prolymphocytic MSL with roundish nuclei, microlymphoblastic and immunoblastic MSL). The former group differs from the latter by the involvement of the epidermis, with hyperplasia of keratinocytes and the disturbance of their differentiation, penetration of tumour cell into the epidermis and by the composition, type and localization of the proliferate. Epidermotropic MSL were much more frequent, affected younger persons, had a longer duration, more widespread skin involvement with polymorphic eruptions.

[A case of nevus verrucosus].

A wart-like nevus in a 49-year-old man, resident of Kaluga Province, is described. The diagnosis has been histologically confirmed.

[The clinical and morphological aspects of lichenoid tissue reactions].

Epidermal basal layer cell vacuolar dystrophy of varying severity was detected in 16 patients with different dermatoses (lichen ruber planus, lupus erythematosus, drug-induced exanthemas, etc.). These changes underlie the lichenoid tissue reactions.

[Acne necrotica].

A 50-year-old female patient with typical symptoms of acne necrotica is described. The eruptions involved seborrheic areas on the skin of the forehead, conchae of the auricles, nose and nasolabial folds, and presented as nodules covered with serous crusts, necrotic foci, and small stamp cicatrices. Histologic findings confirm the clinical diagnosis.