Publications by authors named "E V Vinogradov"
Capsular polysaccharides (CPS) of Acinetobacter baumannii is a virulence factor with diverse structures. CPS are produced by the CPS biosynthesis gene cluster in their K locus (KL). However, CPS variations may occur due to insertion of additional genes from external sources, e.
View Article and Find Full Text PDFStreptococci, Lactococci and Enterococci all produce L-rhamnose-containing cell wall polysaccharides which define Lancefield serotypes and represent promising candidates for the design of glycoconjugate vaccines. The L-rhamnose containing Enterococcal Polysaccharide Antigen (EPA), produced by the opportunistic pathogen Enterococcus faecalis, plays a critical role in normal growth, division, biofilm formation, antimicrobial resistance, phage susceptibility, and innate immune evasion. Despite the critical role of this polymer in E.
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- - The cwps locus in Lactococcus lactis and Lactococcus cremoris encodes the machinery necessary for forming cell wall polysaccharides, which consist of a neutral rhamnan and various side chain oligosaccharides or polysaccharides.
- - The study identifies three new subtypes of C genotype CWPS and utilizes 2D NMR to analyze the unique structures of CWPS from four isolates, revealing distinct rhamnan and polysaccharide components.
- - Findings emphasize the structural diversity of lactococcal CWPS, suggesting that understanding these variations is crucial for improving the robustness of strains used in the fermented food industry against bacteriophages.
Neurofibrillary tangles of tau constitute one of the key biological hallmarks of Alzheimer's disease. Currently, the assessment of regional tau accumulation requires intravenous administration of radioactive tracers for PET imaging. A noninvasive MRI-based solution would have significant clinical implications.
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