[Dynamics of human cardiovascular responses in different periods of long-term exposure in weightlessness].

Purpose of the work was to determine trends in the human cardiovascular function at rest and during LBNP in different periods of short- (8-25 d) and long-term (126-438 d) space flights (SF) using the data of USI and leg occlusive plethysmography. Due to blood redistribution and hypovolemia in the first week on SF, the cardiovascular system decreased the left heart filling and output without loss in myocardium contractility, weakened the renal artery resistance, and increased the maximum capacity of leg veins. In 30-40 days, these developments became more pronounced and were followed by a relative stabilization of hemodynamics at rest.

[Effect of prophylactic device "Braslet" on hemodynamic changes during long-term missions to orbital station Mir].

The benefit from occlusive cuffs (prophylactic device Braslet) to human hemodynamics was evaluated in seven cosmonauts on long-term Mir missions using the ultrasonic technique (Echography and Doppler). Braslet had a positive effect on cosmonauts" state of health during the first month of flight. Improvement of cerebral hemodynamics was attested objectively by reduction of venous congestion.