Publications by authors named "E V Suchkova"
Article Synopsis
- The study aimed to analyze clinical data from patients with non-obstructive ischemic heart disease (IHD) and multifocal atherosclerosis (MFA) in the KAMMA registry, focusing on those who underwent coronary angiography (CAG).
- Out of 1,893 IHD patients, only 8.7% had non-obstructive coronary atherosclerosis (CA), with many affected by MFA in various arteries, especially the brachiocephalic and lower extremity arteries.
- Patients with non-obstructive CA, predominantly women, had fewer traditional risk factors like smoking and diabetes, but higher cholesterol levels; they also experienced less severe IHD and acute coronary syndrome compared to those with obstructive
Aim: A comprehensive assessment of metabolic parameters in patients with non-alcoholic fatty liver disease and based on them the development of prognostic criteria for the development of liver fibrosis.
Materials And Methods: 288 patients with non-alcoholic fatty liver disease at the stage of steatosis were examined. The patients underwent ultrasound examination of the hepatobiliary system using the SONIX OP apparatus (Canada), the FibroMax test, and liver elastography using the AIXPLORER apparatus (France).
In this work, we treated chitin with 2-(azidomethyl)oxirane and successfully involved the resultant azido chitin derivatives in the ultrasound-assisted Cu(I)-catalyzed azido-alkyne click (CuAAC) reaction with propargylic ester of N,N,N-trimethyl glycine. Thus, we obtained novel water-soluble triazole chitin derivatives. The triazole chitin derivatives and their nanoparticles are characterized by a high in vitro antibacterial activity, which is the same or even higher than that of commercial antibiotics ampicillin and gentamicin.
View Article and Find Full Text PDFAim: Study of the effectiveness of differentiated therapy of non-alcoholic fatty liver disease taking into account the clinical and pathogenetic features of its course.
Materials And Methods: 168 patients with non-alcoholic fatty liver disease were examined, 108 of them were women and 60 men aged from 30 to 70 years. For treatment, depending on the characteristics of the course of the disease, 3 groups of patients were formed.
The article reflects current literature data on the epidemiology and risk factors of non - alcoholic fatty liver disease. An important aspect is the description of the modern views of combined lesions of the hepatobiliary tract and small intestine. Disorders of the intestinal microbiota play a special role in the development of non - alcoholic fatty liver disease.
View Article and Find Full Text PDF