Publications by authors named "E V Stepan"

Hypertension and cardiovascular disease are prominent features of chronic kidney disease, and they are associated with premature mortality and progression toward end-stage kidney disease. Renalase, an enzyme secreted predominantly by the kidney and identified in 2005, seems to be one of the missing pieces in the puzzle of heart and kidney interaction in chronic kidney disease by lowering blood pressure and reducing the overactivity of sympathetic tone. This review aims to summarize evidence from clinical studies performed on subjects with CKD in order to explore the value of renalase as a marker and/or a therapeutic target in this disease.

View Article and Find Full Text PDF
Article Synopsis
  • Acute kidney injury (AKI) is a serious complication that can occur in COVID-19 patients, and a study looked at how COVID-19 factors affect its severity and outcomes in 268 patients over 6 months.
  • Key COVID-19 factors linked to AKI severity included lung damage seen on CT scans, oxygen needs, and levels of certain inflammatory markers, though these weren’t good at predicting kidney injury stages.
  • The research found that higher d-dimer levels made it less likely for patients to recover kidney function and that not receiving immunomodulatory treatment led to a greater need for dialysis. Hospital-acquired AKI was more common and often resulted in incomplete recovery compared to AKI present upon admission.
View Article and Find Full Text PDF

Objective: To develop the indications and assess an effectiveness of treatment of patients with ampullary tumors followed by mechanical jaundice.

Material And Methods: There were 26 patients with major duodenal papilla neoplasms for the period 2015-2020 at the Sklifosovsky Research Institute for Emergency Care.

Results: Twenty patients underwent transpapillary interventions: papillosphincterotomy followed by lithoextraction and bilio-duodenal stenting in 4 (15.

View Article and Find Full Text PDF

Objective: To evaluate an efficacy of surgical treatment of patients with benign tumors of the major duodenal papilla.

Material And Methods: For the period from January 2015 to January 2020, sixteenth patients with benign tumors of the major duodenal papilla were treated at the Sklifosovsky Research Institute for Emergency Care. There were 7 men (43.

View Article and Find Full Text PDF

The waste resulted from fish processing industries are discarded into the environment around the world, causing environmental pollution. The main problem of fish oil extracted from waste is the high content in free fatty acids (FFA) which decrease the yield in fatty acids esters during transesterification reactions. Therefore, to correct the fish-oil properties, a new environmentally friendly heterogeneous superacid catalyst (SO/SnO-ZrO) was tested in the esterification reaction of FFA with ethanol.

View Article and Find Full Text PDF