Publications by authors named "E V Sedykh"

Aim      To study the prevalence of senile frailty syndrome (FS), its impact on the functional activity, quality of life, management tactics, and prognosis in patients with acute decompensated heart failure (ADHF).Material and methods  The study included 108 patients (58 men and 50 women, mean age 69.2±10.

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Aim      To evaluate the role of iron deficiency (ID) identified by various criteria, anemia, and the combination of ID and anemia in determining the severity of the clinical course of chronic heart failure (CHF) in a retrospective analysis of data from 498 patients who participated in the ID-CHF-RF Russian multicenter program.Material and methods  ID was diagnosed by the following three criteria established by the European Society of Cardiology (ESC) and the Russian Society of Cardiology (RSC): 1) ferritin concentration <100 μg/l or ferritin concentration 100-299 μg/l in combination with a decreased transferrin saturation (TS) <20%; 2) ID criteria that showed a high sensitivity and specificity when compared with bone marrow morphology (BMM): TS ≤19.8% or serum iron (SI) ≤13 μmol/l; and 3) a composite index including a ferritin concentration <100 μg/l in combination with TS <20% and SI ≤13 μmol/l.

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Article Synopsis
  • The study compares clinical and lab data of chronic heart failure (CHF) patients with iron deficiency (ID) based on two different diagnostic criteria: AHA/ESC/RSC guidelines and a stricter definition involving low transferrin saturation (TSAT) and serum iron levels.
  • Among 498 patients analyzed, ID was identified in 83.1% using AHA/ESC/RSC criteria and 74.5% using the TSAT/serum iron criteria, with many patients meeting both sets of criteria.
  • Those diagnosed with ID based on the TSAT/serum iron criteria experienced more severe CHF symptoms, higher rates of anemia and diabetes, and showed significant differences in lab results and age compared to those diagnosed solely
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Aim    To evaluate the incidence of iron deficiency (ID) in men and women with chronic heart failure (CHF) and to compare clinical and functional indexes in patient with and without ID depending on the gender.Material and methods    An additional analysis of the study "Prevalence of Iron Deficiency in Patients With Chronic Heart Failure in the Russian Federation (ID-CHF-RF)" was performed. The study included 498 (198 women, 300 men) patients with CHF, in whom, in addition to iron metabolism, the quality of life and exercise tolerance (ET) were studied.

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Aim    To evaluate the prevalence of iron deficiency (ID) in Russian patients with heart failure (HF).Material and methods    Iron metabolism variables were studied in 498 (198 women, 300 men) patients with HF. Data were evaluated at admission for HF (97 %) or during an outpatient visit (3 %).

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