Fungal Oto-Mastoiditis- A Rare Presentation in Immunocompetent Individuals.

Fungal oto-mastoiditis is a rare condition and is often associated with host immunodeficiency. It has to be considered as a differential diagnosis among patients presenting symptoms despite an adequate antibacterial therapy. A 23-year-old female presented to the ENT OPD with complaints of occasional left ear discharge, since 2 years which was associated with itching, pain and reduced hearing.

An evaluation of glass beads from the southwestern coastal state of Goa, India, as a potential pollutant in marine ecosystem.

Glass beads laid on the road, mainly used for better visibility, can contribute to harmful anthropogenic waste to the marine environment, and it is a prerequisite to distinguish the chemical properties associated with it. This is the first systematic approach and evaluation of the toxic and non-toxic characteristics of the glass beads from the Indian coastal region (Goa state), which originated from the wearing of road paint over a period. Glass beads ranging from a few hundred to ~ 1000 µm were found on various beaches far from the roadside throughout the coastal state.

Explore & actuate: the future of personalized medicine in oncology through emerging technologies.

Purpose Of Review: The future of medicine is aimed to equip the physician with tools to assess the individual health of the patient for the uniqueness of the disease that separates it from the rest. The integration of omics technologies into clinical practice, reviewed here, would open new avenues for addressing the spatial and temporal heterogeneity of cancer. The rising cancer burden patiently awaits the advent of such an approach to personalized medicine for routine clinical settings.

Feasibility study of total marrow lymphoid irradiation with volumetric modulated arc therapy: clinical implementation in a tertiary care center.

Purpose: Total marrow lymphoid irradiation (TMLI) with volumetric modulated arc therapy (VMAT) is challenging due to large treatment fields with multiple isocenters, field matching at junctions, and targets being surrounded by many organs at risk. This study aimed to describe our methodology for safe dose escalation and accurate dose delivery of TMLI treatment with the VMAT technique based on early experience at our center.

Materials And Methods: Computed tomography (CT) scans were acquired in head-first supine and feet-first supine orientations for each patient with an overlap at mid-thigh.