The Content of ROS in Blood Lymphocytes of Healthy Individuals, Individuals Irradiated as a Result of Chernobyl Disaster and Patients with Prostate Cancer.

The ROS concentration and proliferation activity (Ki67 expression.marker) have been studied in the periphery blood lymphocytes of Moscow and Obninsk citizens, donors, Chernobyl disaster liquidators, inhabitants of the region contaminated after Chernobyl disaster (Klincy) and individuals with prostate cancer. It was shown that ROS concentration in lymphocytes of the liquidators and residents of the polluted region was lowered.

[The Changes of Properties of Blood Peripheral Lymphocytes of Donors and Patients with Prostate Gland Cancer: Reaction of Lymphocytes on Irradiation in vitro].

The oxidative status (ROS), markers activation expression (CD69), proliferation activity (Ki67), proapoptotic antigen (CD95) have been investigated on healthy donors and patients with prostatic gland cancer in human blood lymphocytes. The lymphocyte reaction in vitro on γ-irradiation at different doses (0.05-1.

[The radiosensitivity change after low-dose irradiation, possible mechanisms and regularities].

This paper is a short review of literature data and results of our own investigation into the adaptive response (AR). It was aimed at the analysis of the AR induction, its formation, some mechanisms, its expansion, and universality. It is supposed that a lot of mechanisms, a high variability degree, the absence of this phenomenon in some individuals, as well as dependence on many situations make the AR induction not predictable.