[Vessel-platelet and coagulation components of hemostasis in patients with chronic tubulointerstitial nephritis].

Aim: To study vessel-platelet and coagulation parts of hemostasis system, their correlation with clinical characteristics and activity of chronic tubulointerstitial nephritis (CTIN).

Material And Methods: 128 patients 15 to 65 years of age with CTIN were included in the study. The diagnosis was confirmed morphologically in 42 patients.

[The prognosis and risk factors of cardiovascular complications in patients with chronic glomerulonephritis].

The authors evaluated 10-year prognosis according to SCORE scale and risk factors of fatal cardiovascular diseases in 90 Eropoids aged 53.9+/-0.6 years with a valid diagnosis of chronic glomerulonephritis (CGN) and normal renal function or at the pre-dialysis stage of chronic renal failure.

[Immunogenetic analysis of pathomorphological forms and prognosis of chronic glomerulonephritis].

Aim: To ascertain whether HLA antigens are associated with morphological forms of chronic glomerulonephritis (CGN).

Material And Methods: A retrospective analysis was made of HLA distribution in 122 patients with proliferative and nonproliferative forms of CGN at different stages of fibroplastic transformation and addition of the tubulointerstitial component. Testing of HLA antigens of class I was conducted by lymphocytotoxicity; specificity of DRBI genes was investigated by DNA polymerase chain reaction.

[Immunogenetic analysis of variants of a clinical course and prognosis of chronic glomerulonephritis in the west Siberia].

Aim: To analyze association of HLA antigens with clinical variants of chronic glomerulonephritis (CGN)in 106 patients.

Material And Methods: HLA association with the time of development of terminal chronic renal failure (CRF) from the moment of detection of initial CRF was studied in 80 patients. Determination of HLA of class I was conducted in the lymphocytotoxic test.