Publications by authors named "E V Monakhova"
In 1970, the seventh pandemic of cholera (7 P) reached both Africa and Europe. Between 1970 and 2011, several European countries reported cholera outbreaks of a few to more than 2,000 cases. We report here a whole-genome analysis of 1,324 7 P V.
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- The seventh cholera pandemic has significantly impacted Africa, with its origins and spread not fully understood.
- Researchers analyzed genomic data from 1070 cholera O1 isolates across 45 African countries over 49 years, finding that past epidemics came from a single expanded lineage introduced multiple times since 1970.
- Recent introductions consisted of drug-resistant sublineages from Asia, emphasizing the need for targeted cholera control measures based on the identified patterns of spread.
We performed an electron microscopic study of the small intestine of suckling rabbits infected with cholerogenic and non-cholerogenic strains nonO1/nonO139 Vibrio cholerae. Cholerogenic strain induced mostly hydropic degeneration of the epithelium typical of cholera toxin effect, while non-cholerogenic strain induced the formation of lacunae along the borders of adjacent epithelial cells typical of hemagglutinin/protease effect. In both cases, reduction of microvilli, destruction of intracellular organelles, two types of mitochondrial reaction (condensation and swelling with destruction of cristae), appearance of myelin figures, defects in the capillary walls, and activation of pinocytosis were observed.
View Article and Find Full Text PDFVibrio parahaemolyticua and Vobrio alginolyticus are phylogenetically closely-related species. They have common ecological niches, same cultural features and similar biochemical characteristics. The phenotype variability and taxonomy similarity of strains of these species impedes differentiation of Vibrio parahaemolyticua and Vobrio alginolyticus according biochemical characteristics.
View Article and Find Full Text PDF[Collection of Vibrio parahaemolyticus species members: phenotypic and genotypic characteristics].
Zh Mikrobiol Epidemiol Immunobiol
April 2015
Aim: Formation of Vibrio parahaemolyticus collection according to modern methodical opportunities and understanding of causative agent biology.
Materials And Methods: Traditional biochemical tests and PCR-testing of species-specific genes were used to confirm species membership. Catalase, DNAse, proteolytic and tweenase activity was determined by common methods.