DTI-MRI at 2 days after spinal cord injury accurately predicts long-term locomotor function recovery in rats.

Objective: Spinal cord injury (SCI) damages an individual's sensory, motor, and autonomic functions and represents a social emergency, mostly in developed countries. Accurate and timely diagnosis of the severity of SCI must be carried out as quickly as possible to allow time for drug and therapy testing in the early stages after injury.

Materials And Methods: Male Dark Agouti (DA) rats underwent spinal cord cryoinjury at the T13 level of the spine.

CSF - injected contrast medium enhances post-traumatic spinal cord cysts. An experimental study in rats.

Objective: Spinal cord injury (SCI) is still one of the most challenging problems in neurosurgical practice. One of the major obstacles to neural regeneration following trauma is the formation of glial scarring and post-traumatic cysts which acts against proper growth of axons through the site of injury. Cerebrospinal fluid (CSF) delivery of bioactive agents into cystic cavities could represent a promising therapeutic strategy.