Publications by authors named "E V Lebedev"
Eusociality, characterized by reproductive division of labor, cooperative brood care, and multi-generational cohabitation, represents a pinnacle of complex social evolution, most notably manifested within the Hymenoptera order including bees, ants, and wasps. The molecular underpinnings underlying these sophisticated social structures remain an enigma, with noncoding RNAs (ncRNAs) emerging as crucial regulatory players. This article delves into the roles of ncRNAs in exerting epigenetic control during the development and maintenance of Hymenopteran eusociality.
View Article and Find Full Text PDFBees represent not only a valuable asset in agriculture, but also serve as a model organism within contemporary microbiology. The metagenomic composition of the bee superorganism has been substantially characterized. Nevertheless, traditional cultural methods served as the approach to studying brood combs in the past.
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- - This study explores how repetitive DNA sequences influence the social structures of honeybees, focusing on two subspecies and their genomic differences.
- - While much is known about the Notch signaling pathway in caste formation, the specific elements that regulate gene expression (cis-regulatory sequences) are still not fully identified.
- - The research highlights a unique chromatin state linked to these repetitive elements, suggesting they might play a role in developing new regulatory functions, even though their impact on gene expression during caste differentiation was minimal.
Article Synopsis
- This review compares early embryonic development in Protostomia and Deuterostomia, highlighting that Protostomia have a deterministic mosaic pattern, while Deuterostomia have an indeterminate regulatory pattern of development.
- It emphasizes that despite these differences, both groups share common transcriptional mechanisms that suggest evolutionary connections, especially in functional genomics.
- The objective is to clarify the similarities and differences in their transcriptional regulatory strategies, contributing to evolutionary biology and developmental biology, and paving the way for future research.
Aim To study prognostic significance of the degree of stenosis of carotid and lower-extremity arteries (LEA) in patients at high and very high risk of cardiovascular complications (CVC).Material and methods The study included men and women aged 40-67 years at high and very high risk of CVC. Duplex ultrasound scanning of carotid arteries and LEA was performed for all patients.
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