[Ability of energy metabolism of cells to activate repair of its genetic material after radiation damage].

A new hypothesis on a mechanism of action of the radioprotective and medical preparations involving the activation of oxidative phosphorylation and biogenesis of mitochondria which provides the increase of dimension and rapidity of the cellular reparation has been suggested. A previously unknown property of mitochondrions to determine a cellular homeostasis has been found. An activation of oxidative phosphorylation of mitochondria is a way of cellular protection against extreme conditions (namely, against radiation exposure and tumor formation).

[The destruction of microscopic organisms by their irradiation with a special form of UHF electromagnetic signals].

Electromagnetic signals of special form produced by an ultra-high frequency generator were used to destroy various microorganisms: baker's yeast; blue-green alga Nostoc muscorum; mold fungus; and two flagellates, plant flagellate Euglena gracilis and an animal flagellate parasitizing on humans. The control samples before irradiation and experimental samples damaged and destroyed by irradiation were examined on a microscope with a computer system of image analysis. The results are presented as computer graph images.

[Measurement of proinsulin, insulin and C-peptide in human blood by high performance liquid chromatography].

The technique of measuring insulin, proinsulin, and C-peptide in human blood by high-pressure liquid chromatography is described. Donors, subjects with abnormal glucose tolerance, and patients with type I diabetes were examined. The main advantage of the method over radioimmunoassay and enzyme immunoassay is the possibility of simultaneous differentiated measurement of human insulin and animal hormone administered parenterally, and separation of insulin and its precursor on the basis of difference in molecular weight and charge of molecules.

[Prognostic significance of determining cathepsin B activity in malignant ovarian tumors].

Malignant tumors derived from 60 patients with primary ovarian cancer were assayed for lysosomal cysteine proteinases--cathepsins B and L (Cat B, Cat L) and lysosomal aspartyl proteinase--cathepsin D (Cat D) as compared with benign ovarian tumors in controls. Malignant ovarian tumors exhibited significantly increased Cat B and Cat L activity (18.5- and 9-fold, respectively, p < 0.