Publications by authors named "E V Dubynina"
The influence of subchronic administration of nootropic drugs (piracetam, phenotropil, meclophenoxate, pantocalcine, semax, nooglutil) on the brain-derived neurotrophic factor (BDNF) content in hippocampal and cortical tissues in mice with different exploratory behavior--high efficacy (HE) against low efficacy (LE)--in cross-maze test has been studied. The initial BDNF concentration in hippocamp (but not in cortex) of control HE mice was higher than that in LE mice (LE, 0.091 +/- 0.
View Article and Find Full Text PDFArticle Synopsis
- Semax is a heptapeptide that enhances learning and has neuroprotective effects when applied intranasally.
- A single dose of Semax significantly increases BDNF protein levels and activates trkB in the hippocampus of rats, indicating enhanced neural signaling.
- Rats treated with Semax exhibited improved cognitive functions, evidenced by increased conditioned avoidance reactions.