Pupils from the mining-trade secondary schools aged, 17-18 from different towns of Donbass were examined for the state of immunologic reactivity, as evidenced by the peripheral blood content of leucocytes, level of Igs A, M, G, as well as cytotoxicity of blood plasma. The results obtained suggest weakening of immunological reactivity in the examined populations, with the degree of the immunological reactivity impairement being higher in Donetsk as compared with more clean ecological zone Selidovo, which fact suggests a negative influence the complex of harmful environmental factors has on human organism. The above age group warrants further study; there is also the need to devise approaches toward immunocorrecting therapy for such contingents.
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