[Characteristics of toxigenic properties of Myrothecium cinctum (Corda) sacc., 1886 and Myrothecium commune pidopl., 1969].

The comparative study of toxigenic potential of Myrothecium cinctum (12 strains) and Myrothecium commune (7 strains) was conducted. The ability to produce the complex of macrocyclic trichothecenes (MCTC) presented in ethanol soluble fraction (ESF), as well as fungistatic activity against yeasts test-cultures (strains Saccharomyces vini "Feodosia" and Candida stellatoidea 62) and rabbit skin test were evaluated. It was established that ESF output varied within wide limits in all studied strains of both species but it was significantly lower in M.

[Some variants of premanifesting disorders in attack-like schizophrenia].

Objective: To investigate a spectrum of disorders preceding the development of manifesting psychosis in the aspect of their topology and possible prognostic value.

Material And Methods: Authors examined 60 outpatients, 21 women and 39 men, aged from 22 to 34 years. All patients were diagnosed with attack-like progressive schizophrenia.

[Study of specificity of fungistatic effect of trichothecene mycotoxins].

In attempt to realize the purposeful search of highly sensitive and highly specific microbial test-cultures the authors studied the ratio between selected before species of yeast to the wide set of different mycotoxins including macrocyclic trichothecenes (T-2 toxin, HT-2 toxin, T-2 triol, T-2 tetraol, NT-1 toxin, NT-2 toxin, fusarenon-X, diacetoxyscirpenol, deoxynivalenol, trichothecin, trichothecolon, neosolaniol, verrucarin A, roridin A, roridin H, aflatoxins, B1, B2, G1 and G2, sterigmatocystin, patulin, fusaric acid, ochratoxin A, zearalenon and their derivatives). It was supposed to define borders of specific sensitivity of test-cultures. The value of minimal inhibiting concentration (MIC) of mycotoxins, which caused fungicide action in respect of the investigated yeast strains, was used as the estimation criterion.

[Mycotoxins: past, present and future].

The paper deals with historical information concerning the investigation of mycotoxins and mycotoxicoses at the Institute of Microbiology and Virology of the NAS of Ukraine, main results of the works fulfilled for the last 25 years and possible trends of further investigations.