Publications by authors named "E Upton"

Age-related changes in cognitive and biological processes mean that older adults show markedly lower performance on cognitive assessments than younger adults. Characterizing the precise nature of age-related differences in cognitive performance and whether they vary as a function of key demographic characteristics has been challenging due to small effect sizes, underpowered samples, and blunt analysis methods. In the present study, we address these issues by using a massive cross-sectional data set of approximately 750,000 English-speaking participants who completed at least one battery from the NeuroCognitive Performance Test.

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Objectives: Intrusive thoughts and images in Health Anxiety are poorly understood. The current study aims to explore the rates and nature of health-related intrusive thoughts and images in people with and without Health Anxiety.

Design: We used a cross-sectional interview and survey design recruiting 82 participants (Health Anxiety: n = 37; control: n = 45).

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Background: Speech comprehension impairment in post-stroke aphasia is influenced by speech acoustics. This study investigated the impact of speech rhythm (syllabic isochrony) and rate on comprehension in people with aphasia (PWA). Rhythmical speech was hypothesised to support comprehension in PWA by reducing temporal variation, leading to enhanced speech tracking and more appropriate sampling of the speech stream.

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Listeria monocytogenes is a foodborne intracellular bacterial model pathogen. Protective immunity against Listeria depends on an effective CD8 T cell response, but very few T cell epitopes are known in mice as a common animal infection model for listeriosis. To identify epitopes, we screened for Listeria immunopeptides presented in the spleen of infected mice by mass spectrometry-based immunopeptidomics.

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Introduction: Sleep difficulties are common amongst university students and are associated with mental illness and reduced wellbeing. This paper reports a pilot study of Cognitive Behavior Therapy for Insomnia (CBT-I) tailored specifically for university students. It was hypothesized that the intervention would be feasible, acceptable, and improve sleep, anxiety, depression, and wellbeing.

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