Publications by authors named "E Unlu"

Sequence diversity is one of the major challenges in the design of diagnostic, prophylactic, and therapeutic interventions against viruses. DiMA is a novel tool that is big data-ready and designed to facilitate the dissection of sequence diversity dynamics for viruses. DiMA stands out from other diversity analysis tools by offering various unique features.

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Motivation: Monitoring the genomic evolution of Plasmodium falciparum-the most widespread and deadliest of the human-infecting malaria species-is critical for making decisions in response to changes in drug resistance, diagnostic test failures, and vaccine effectiveness. The MalariaGEN data resources are the world's largest whole genome sequencing databases for Plasmodium parasites. The size and complexity of such data is a barrier to many potential end users in both public health and academic research.

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Ethnopharmacological Relevance: Morus alba L., mulberry, has played a significant role in providing food, medicine, and materials throughout human history. From its historical importance to its diverse cultural uses, mulberry remains a versatile and valuable resource, enriching various aspects of human life across civilizations.

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Article Synopsis
  • The study investigates how developmental changes affect peroxisome activity, focusing on gene expression patterns in specific metabolic pathways across developmental stages in plants.
  • It finds that photorespiration is more prominent in adult leaves compared to juvenile stages, with additional pathways related to reactive oxygen species (ROS) and polyamine catabolism becoming more active as leaves mature.
  • Key genes, including those related to GABA synthesis, are upregulated in older seedlings, suggesting that GABA plays a role in regulating peroxisome fission during leaf differentiation.
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Article Synopsis
  • The study compared the capsular volume of patients with shoulder instability to those without using MR arthrography, aiming to create a reliable screening method.
  • In a retrospective analysis of 21 patients with shoulder instability and 21 controls, volumetric measurements of various shoulder components were taken from 3D MR images.
  • Results showed that the instability group had a significantly larger total joint volume and greater volumes in specific shoulder areas compared to the control group, suggesting that 3D volumetric assessment can aid in clinical evaluations and treatment decisions for shoulder instability.
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