Publications by authors named "E Ucgul"
Article Synopsis
- The study investigates the impact of sarcopenia (muscle loss) and systemic inflammation on the effectiveness of immunotherapy in cancer patients, considering factors like Eastern Cooperative Oncology Group Performance Status (ECOG PS).
- It involved 100 patients who received immune checkpoint inhibitors, analyzing various systemic inflammation markers to evaluate their relationship with overall survival (OS) and progression-free survival (PFS).
- Results show that sarcopenia and hypoalbuminemia are significant factors linked to poorer survival outcomes, suggesting that monitoring sarcopenia could potentially improve patient prognoses, although more research is necessary to confirm these findings.
Painless legs and moving toes (PoLMT) is a rare variant of painful legs and moving toes (PLMT). The difference is the absence of pain, which is usually hard to manage in PLMT. An involuntary movement in the toes is a compound of both.
View Article and Find Full Text PDFDynamic changes in the blood-based biomarkers could be used as a prognostic biomarker in patients treated with immune checkpoint inhibitors (ICIs), although the data are limited. We evaluated the association between the neutrophil−lymphocyte ratio (NLR) and early NLR changes with survival in ICI-treated patients. We retrospectively evaluated the data of 231 patients with advanced-stage cancer.
View Article and Find Full Text PDFBackground: The albumin-globulin ratio (AGR) could be a prognostic biomarker in patients with cancer, although the data is limited in patients treated with immune-checkpoint inhibitors (ICIs).
Objectives: We aimed to evaluate the association between AGR and survival in ICI-treated patients.
Methods: The data of 212 advanced-stage patients were retrospectively evaluated in this cohort study.
Background: We compared the new outpatient clinic referrals during the first 10 months of the COVID-19 pandemic with the year before.
Methods: We compared baseline characteristics of the 2208 new referrals in 2020 (n=922) and 2019 (n=1286) with Χ and Mann-Whitney U tests and calculated ORs with binary logistic regression. To evaluate the expected changes in the cancer survival secondary to stage migration, we used the 5-year survival data of Survival, Epidemiology and End Results (SEER) Program 2010-2016.