Publications by authors named "E Twizeyimana"

Article Synopsis
  • The study addresses the challenges faced by struggling medical and nursing students by implementing a peer mentorship strategy to enhance their well-being, self-determination, school connectedness, and academic performance.
  • Utilizing a mixed-methods approach, the research will evaluate the impact of this mentorship intervention on students’ subjective vitality, school engagement, and academic records based on two cumulative continuous assessment test (CAT) scores.
  • Aimed at filling knowledge gaps in Nigeria and Rwanda, the research will contribute valuable insights into effective interventions for improving the experiences of low-performing medical and nursing students.
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Article Synopsis
  • Human Immunodeficiency Virus (HIV) causes Acquired Immunodeficiency Syndrome (AIDS) with significant health risks, especially in low- and middle-income countries due to increasing drug resistance and treatment challenges.
  • Progress is being made in developing new antiretroviral (ARV) drugs that target various HIV components and mechanisms, currently undergoing clinical trials, with specific compounds being discussed in terms of their efficacy and safety.
  • Continuous efforts are vital for advancing the discovery of innovative ARV treatments to mitigate drug resistance and improve patient outcomes, as there is currently no cure or vaccine for HIV.
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Background: Surgical volume is a surgical indicator that was described in the Lancet Commission on Global Surgery (LCoGS) and the World Bank World Development Indicators as an important metric for tracking the delivery of surgical care.

Objectives: We aimed to characterize the reports on surgical volume (SV) in the existing literature by using a systematic review to assess studies that examine surgical procedures as a ratio of a population (procedures/100,000 population).

Methods: The PRISMA guideline was employed in the systematic review of articles that addressed the measurement of SV in low- and middle-income countries (LMICs), with the primary outcome of surgical procedures/100,000 population.

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High-efficiency endosomal escape of drug delivery nanocarriers for glutathione-based reduction-responsive drug release in cytoplasm can significantly enhance the therapeutic efficacy of the loaded therapeutic drugs. In this report, we develop the polymer prodrug micelles self-assembled from the amphiphilic block copolymer prodrug, PEG--P(CPTM--ImOAMA), consisting of poly(ethylene glycol) (PEG) and copolymerized segments of disulfide bond-linked camptothecin methacrylate monomer (CPTM) and 1-(1H-imidazole-4-yl)-2-(octylamino)-2-oxoethyl methacrylate (ImOAMA). After cellular internalization through endocytosis, PEG--P(CPTM--ImOAMA) micelles are trapped in endosomes inside the tumor cells.

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