Five year study of rotavirus gastroenteritis in Bulgaria.

We tested by electron microscopy 7,530 samples from children admitted to different hospitals in Sofia between February 1981 and February 1986; from these, rotaviruses were found in 725 (9.6%) faecal samples. Electron microscopic analysis of 264 samples from 181 children admitted to the hospital of infectious diseases in Shumen between December 1984 to February 1986 revealed rotaviruses in 120 (66.

The effect of exogenous histone on the synthesis of DNA, RNA and proteins in Coxsackie B4 virus infected cells.

The incorporation of labelled precursors of DNA, RNA and proteins in F. cells infected with Coxsackie B4 virus has been traced both in the presence and absence of total histone from nucleated erythrocytes during the infectious process. In comparison with the virus infection alone, the exogenous histone supressed the incorporation of 3H-thymidine in early hours and the incorporation of 3H-uridine and 14C-leucine in the 9th hour after virus infection.