Publications by authors named "E Toselli"
Article Synopsis
- Studies show that individuals with Multiple Sclerosis (MS) often experience high rates of depression, affecting their overall well-being and physical functions.
- This study assessed the effectiveness of Eye Movement Desensitization Reprocessing (EMDR) therapy—called DeprEND—on reducing depression among 13 MS patients, finding significant improvements after treatment and at a 3-month follow-up.
- Results indicated high adherence to the treatment, with notable decreases in depressive symptoms and some brain function changes, suggesting EMDR could be a promising and affordable option for enhancing mental health in MS patients.
The localization of condensin along chromosomes is crucial for their accurate segregation in anaphase. Condensin is enriched at telomeres but how and for what purpose had remained elusive. Here, we show that fission yeast condensin accumulates at telomere repeats through the balancing acts of Taz1, a core component of the shelterin complex that ensures telomeric functions, and Mit1, a nucleosome remodeler associated with shelterin.
View Article and Find Full Text PDFThe COVID-19 outbreak and the restrictions that have been enforced by the health authorities are having a profound psychological impact on the population. Many people, including the students, faced forced modifications to their daily lives and this prompted the need for scalable strategies to promote resilience. We designed an online community intervention for psychology students and recent alumni aimed to promote functional coping strategies through openness and cognitive flexibility.
View Article and Find Full Text PDFCondensins are genome organisers that shape chromosomes and promote their accurate transmission. Several studies have also implicated condensins in gene expression, although any mechanisms have remained enigmatic. Here, we report on the role of condensin in gene expression in fission and budding yeasts.
View Article and Find Full Text PDFOligodeoxyribonucleotide ligation to single-stranded cDNA (SLIC) and polymerase chain reaction (PCR) techniques were used to clone an entire dog gastric lipase (DGL) cDNA. The size of the cDNA is confirmed by Northern blot analysis. The DGL is synthesized as a 379-amino acid mature polypeptide with a molecular mass of 43176 Da which is preceded by a 19-amino acid signal sequence located at the NH2-terminus.
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