Publications by authors named "E Terzi"
New series of benzimidazole-1,2,4-triazole derivatives were designed, synthesized, and characterized using H-NMR, C-NMR, and HRMS. These compounds were evaluated for anticancer activity toward HTB-9 bladder and HT-29 colorectal cancer cell lines. Compounds 7h and 7ı were found to be the most active against HTB-9 cell line, with IC 6.
View Article and Find Full Text PDFOne of the preferred treatments for bladder cancer, one of the most common cancers worldwide, is cisplatin-based chemotherapy. Since most tumor cells show cisplatin resistance, it is very important to discover new agents without adverse side effects. β-arbutin, a hydroquinone-β-D-glucopyranoside, has biological properties such as antioxidant, antimicrobial, anti-inflammatory, and anticancer, and is a phytochemical widely used as a skin whitener.
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- Danofloxacin, a fluoroquinolone antibiotic, is effective against bacterial infections in fish, but its pharmacokinetics vary based on fish size, impacting its medicinal effectiveness.!* -
- A study conducted on rainbow trout demonstrated that larger fish have higher plasma concentrations and overall drug efficacy of danofloxacin compared to smaller fish, with measurements taken after oral administration.!* -
- While larger fish show increased therapeutic efficacy, their higher drug concentrations in tissues raise concerns about potential residue and withdrawal time for safe consumption.!*
Objective: The aim of this study was to determine the plasma pharmacokinetics of oxytetracycline (OTC) in rainbow trout () of different body sizes.
Methods: The research was carried out on three groups as small (30-50 g), medium (90-110 g) and large (185-215 g) body sizes at 8 ± 0.5 °C.