Publications by authors named "E Takahashi"

In patients with renal masses, when intervention is warranted, partial nephrectomy is preferred when feasible, especially for T1 renal masses. Thermal ablation, however, has become an accepted alternative treatment of small renal neoplasms with excellent oncologic outcomes. The National Comprehensive Cancer Network guidelines include thermal ablation as a treatment strategy for managing T1a and select T1b masses.

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  • Transradial arterial access offers advantages over femoral access in coronary interventions, including reduced bleeding, improved patient comfort, and shorter hospital stays, leading to increasing interest in its use for peripheral vascular procedures.
  • Despite its benefits, challenges remain, and ongoing development of specialized equipment is necessary for effective use in these interventions.
  • Current studies suggest that transradial access is generally safe and associated with fewer complications, but further large-scale randomized trials are needed to fully understand its impact on patient outcomes and to identify suitable patient selection criteria.
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Nuclear clearance and cytoplasmic aggregation of TAR DNA-binding protein of 43 kDa (TDP-43) are pathological hallmarks of amyotrophic lateral sclerosis (ALS) and its pathogenic mechanism is mediated by both loss-of-function and gain-of-toxicity of TDP-43. However, the role of TDP-43 gain-of-toxicity in oligodendrocytes remains unclear. To investigate the impact of excess TDP-43 on oligodendrocytes, we established transgenic mice overexpressing the ALS-linked mutant TDP-43 in oligodendrocytes through crossbreeding with Mbp-Cre mice.

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  • - The modified Attitudes Toward Health Care Teams Scale (mATHCTS) is a reliable 14-item questionnaire designed to evaluate how participants perceive the effects of interprofessional collaboration in health care.
  • - Research using item-response theory (IRT) was conducted on 180 health and welfare university students to analyze the scale's item characteristics like difficulty and discrimination, showing that the mATHCTS is effective in identifying attitudes toward health care teams.
  • - The study found that while the test-response function (TRF) increased consistently with ability, the test-information function (TIF) indicated that measurement accuracy decreased as total scores rose, affirming that the mATHCTS identifies participants with lower scores effectively.
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The implementation of home-care robots is sometimes unsuccessful. This study aimed to explore factors explaining people's willingness to use home-care robots, particularly among care recipients and caregivers. Surveys were conducted in Japan, Ireland, and Finland.

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