Publications by authors named "E Taha"

The present work focuses on the production of sildenafil co-evaporates loaded emulgels as topical dosage forms for the treatment of premature ejaculation and erectile dysfunction. Topical administration of sildenafil citrate (SILD) co-evaporates is expected to improve the bioavailability profile of the drug and to avoid the severe side effects accompanying the traditional SILD dosage forms, especially for prohibited cardiovascular cases. Firstly, the solubility of SILD was improved via solid dispersion via co-evaporation technique using PEG-5KDa and PVP-K90 as hydrophilic carriers.

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Introduction: Haemophilic arthropathy (HA) is the most frequent complication in people with haemophilia (PWH). MRI is the gold standard to assess HA, however, there are limitations to its use in low-resourced areas.

Aim: Primary; to compare clinical-functional, laboratory, and ultrasonographic joint scores with MRI scores to determine a reasonable alternative to MRI.

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Ethnopharmacological Relevance: Morus alba L., mulberry, has played a significant role in providing food, medicine, and materials throughout human history. From its historical importance to its diverse cultural uses, mulberry remains a versatile and valuable resource, enriching various aspects of human life across civilizations.

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  • Novel univariate and chemometrics-aided UV spectrophotometric methods were developed to accurately estimate a mixture of olanzapine, fluoxetine HCL, and its impurity without prior separation, achieving high accuracy (98-102%) and precision (<2%).
  • The study employed advanced techniques like Partial Least Squares (PLS) and Artificial Neural Networks (ANNs) that improved model reliability using Latin hypercube sampling, resulting in lower limits of quantification (LOQs) and minimal prediction errors for all substances.
  • The methods demonstrated a significant eco-friendly approach, scoring high in environmental assessments (NEMI, GAPI, and RGB 12), indicating effective compliance with green analytical chemistry principles.
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  • * Surfactants like Tween 80 and SDS were found to improve the dispersion of MWCNTs in the epoxy, while gamma irradiation changed thermal stability and viscoelastic properties, leading to enhanced crosslinking and varying recovery behaviors.
  • * The study concluded that radiation treatment and surfactant use can optimize nanoparticle composites, improving mechanical performance and shape recovery, which is crucial for satellite applications.
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