Publications by authors named "E T Wei"
Background: Incidence data on Facial Nerve Disorders (FND) and Bell's palsy are currently limited. Prior epidemiological studies have estimated the incidence rate of Bell's palsy to be between 11 and 53/100,000 individuals, although the most cited incidence data are from single regions or municipalities, many of which are outdated from several decades ago.
Methods: This was a retrospective cohort study of US adults from 2007 to 2022 using the Merative™ Marketscan® Research Databases.
Glioma Amplified Sequence 41 (GAS41) is a chromatin-associated protein that belongs to the YEATS domain family of proteins and is frequently amplified in various tumors. However, its biological function and carcinogenic mechanism in gliomas are not fully understood. In this study, we revealed that GAS41 was upregulated in human glioma tissues and cell lines, and higher expression of GAS41 was significantly associated with poor clinical prognosis.
View Article and Find Full Text PDFBackground: The rarity of optic nerve sheath meningiomas (ONSMs) complicates the guidelines surrounding optimal treatment strategies and prognostic factors. There are limited data on the visual outcomes of those treated with radiotherapy versus those observed without treatment. This study aimed to characterize the clinical and radiographic presentations of patients diagnosed with ONSMs and to identify factors predicting improvement in visual function after treatment.
View Article and Find Full Text PDFArticle Synopsis
- Chemotherapy significantly improves prognosis for colorectal cancer patients, but resistance to drugs like 5-Fluorouracil (5-FU) is a growing problem.
- Research identified that nucleotide metabolism may play a key role in both cancer progression and drug resistance, leading to the development of a risk score model to predict patient outcomes.
- The study found that the gene NDUFA4L2 enhances colon cancer cell growth and movement, contributing to resistance against 5-FU, highlighting its potential as a target for improving treatment strategies.