Publications by authors named "E T Salinaro"
Congenital pulmonary airway malformations (CPAMs) are a heterogeneous group of hamartomatous cystic and noncystic lung lesions that result from early airway maldevelopment. Usually they are distinguished according to Stocker's classification in type 0, 1, 2, 3 and 4. We present the case of a 2 weeks old baby who was admitted to hospital with RDS symptoms and left pleural effusion: X rays and CT were suggestive for a pulmonary cystic lesion with pleural complications.
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- Childhood survivors of acute lymphoblastic leukaemia (ALL) show a significantly higher prevalence of non-alcoholic fatty liver disease (NAFLD) compared to healthy controls (39.6% vs 11.7%).
- Patients with NAFLD are also observed to be more obese and insulin resistant, alongside experiencing early cardiovascular dysfunction, evidenced by lower heart function metrics compared to controls.
- Preventive measures focused on reducing visceral fat and promoting healthy lifestyle choices are strongly recommended for ALL survivors to mitigate risks associated with metabolic syndrome and cardiovascular issues.
Assessment of Disease Activity in Small Bowel Crohn's Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score.
Gastroenterol Res Pract
January 2016
Objectives. To retrospectively compare the results of the MRIA (magnetic resonance index of activity) with a modified MRIA (mMRIA), which was calculated excluding from MRIA formula the data of relative contrast enhancement (RCE). Materials and Methods.
View Article and Find Full Text PDFDue to their ballistic precision, apoptosis induction by protons could be a strategy to specifically eliminate neoplastic cells. To characterize the cellular and molecular effects of these hadrons, we performed dose-response and time-course experiments by exposing different cell lines (PC3, Ca301D, MCF7) to increasing doses of protons and examining them with FACS, RT-PCR, and electron spin resonance (ESR). Irradiation with a dose of 10 Gy of a 26,7 Mev proton beam altered cell structures such as membranes, caused DNA double strand breaks, and significantly increased intracellular levels of hydroxyl ions, are active oxygen species (ROS).
View Article and Find Full Text PDFBackground: The identification of factors mediating the transition of lung fibroblasts into myofibroblasts is considered fundamental in the comprehension of abnormal reparative processes. Bradykinin, a mediator known for its proinflammatory action, is able to induce cytokine production and contractility in fibroblast cultures.
Objectives: In this study the ability of bradykinin to drive fibroblast into a myofibroblast phenotype at the cellular and molecular level was evaluated.