Publications by authors named "E T Obishakin"
Background: Bluetongue virus serotype 3 (BTV-3) was detected for the first time in cattle and sheep in southern England in 2023, the first UK BTV incursion for more than 15 years. Clinical signs were not observed, yet severe clinical disease and mortality were reported during recent BTV-3 outbreaks in northern Europe.
Methods: To investigate the clinical disease and infection kinetics associated with this UK BTV-3 strain, five British sheep were infected with a UK BTV-3 isolate using Culicoides biting midges.
Article Synopsis
- - The COVID-19 pandemic has led to 7.1 million deaths globally, with Nigeria reporting its first case on February 27, 2020, resulting in 267,173 infections and 3,155 deaths by July 2024.
- - Initially, Nigeria had limited public health lab capabilities for COVID-19 diagnosis, but the National Veterinary Research Institute (NVRI) leveraged its resources and expertise to process over 33,000 samples across five states within six months.
- - Collaborative projects were established among NVRI, the Nigerian Centre for Disease Control, and other sectors, focusing on One Health grants to improve surveillance for coronaviruses and enhance pandemic preparedness through inter-sectoral cooperation.
The diversity in genome resources is fundamental to designing genomic strategies for local breed improvement and utilisation. These resources also support gene discovery and enhance our understanding of the mechanisms of resilience with applications beyond local breeds. Here, we report the genome sequences of 555 cattle (208 of which comprise new data) and high-density (HD) array genotyping of 1,082 samples (537 new samples) from indigenous African cattle populations.
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- Sarcocystis are protozoa that require both a predator (like humans) and a prey (like pigs) in their life cycle, with S. suihominis specifically affecting pigs as intermediate hosts.
- Ingesting raw or undercooked pork containing these parasites can cause gastroenteritis in humans, leading to symptoms like nausea and diarrhea, and can spread the parasite through feces.
- This study is notable for identifying S. suihominis in Nigeria for the first time using genetic analysis, highlighting a public health risk linked to pigs and poor hygiene practices on local farms.
Background: The genomes of indigenous African cattle are composed of components with Middle Eastern (taurine) and South Asian (indicine) origins, providing a valuable model to study hybridization and to identify genetic barriers to gene flow. In this study, we analysed indigenous African cattle breeds as models of hybrid zones, considering taurine and indicine samples as ancestors. In a genomic cline analysis of whole-genome sequence data, we considered over 8 million variants from 144 animals, which allows for fine-mapping of potential genomic incompatibilities at high resolution across the genome.
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