Publications by authors named "E T Hostnik"
Background: Human patients with Ehlers-Danlos syndrome (EDS) are categorized into subtypes based on causative genetic variants and phenotypes. The classical form of EDS, primarily caused by variants in COL5A1 or COL5A2, is a very common subtype in people but is poorly characterized in dogs.
Objective: Describe likely causal COL5A1 variants in dogs with classical EDS, summarize clinical histories, discuss potential disease mechanisms, and draw conclusions about disease prognosis.
Chronic osteoarthritis caused by infection in a captive sand gazelle.
J Vet Diagn Invest
November 2024
Article Synopsis
- Osteoarthritis is a significant health issue in geriatric gazelles, and a case study highlights a male sand gazelle suffering from progressive osteoarthritis of the right tarsus, resulting in chronic lameness.
- Serial biopsies and diagnostic imaging revealed the presence of pyogranulomatous dermatitis and a bacterial infection that is typically associated with cattle but had not been documented in other species, including gazelles.
- Despite various treatments, the condition worsened, leading to the animal's euthanasia, where postmortem analysis showed extensive tissue damage and revealed a new possibly infectious bacterium that could be a factor in chronic osteoarthritis in gazelles.
Objective: The objective of this study was to optimize an MRI-based diffusion tensor imaging (DTI) protocol for imaging the plantar nerves at the level of the tarsus in normal equine limbs.
Sample: 12 pelvic cadaver limbs from horses without evidence of proximal suspensory pathology were imaged with a 3T MRI system.
Methods: For diffusion-weighted imaging, b values of 600, 800, and 1,000 s/mm2 were tested.
Imaging diagnosis: Disseminated hemangiosarcoma in a Welsh pony.
Vet Radiol Ultrasound
September 2024
A 16-year-old pony gelding presented with epistaxis and a head tilt. Referral skull radiographs suggested an ethmoid hematoma. Concurrent neurologic abnormalities prompted contrast-enhanced CT of the head and cranial neck, revealing numerous hyperattenuating masses throughout the brain and paranasal sinuses, along with a large osteolytic mass in the second cervical vertebra.
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- - Two echidnas at a zoo experienced issues like anorexia and lethargy, with one dying shortly after being transferred to another facility where severe thyroid problems were found postmortem.
- - The second echidna was euthanized after a CT scan revealed a mass compressing important blood vessels, which was later diagnosed as thyroid adenocarcinoma.
- - These cases highlight the importance of using IV contrast and CT scans for diagnosing thyroid diseases in echidnas.