Publications by authors named "E Svarch"
Introduction: Total splenectomy in sickle cell disease is related to a high risk of fulminant sepsis and increased incidence of other events, which have not been reported in patients with partial splenectomy. In this study we examined the patients with sickle cell disease and partial splenectomy and compared the clinical and laboratory results with non-splenectomized patients.
Material And Methods: We studied 54 patients with sickle cell disease who underwent partial splenectomy in childhood from 1986 until 2011 at the Institute of Hematology and Immunology.
Article Synopsis
- Treatment of hematologic disorders like sickle cell disease and aplastic anemia is challenging in low-income countries due to resource limitations.
- Pediatric hematologists from 15 LIC reported effective use of low-dose hydroxyurea for sickle cell disease, which helped minimize pain crises.
- Patients with severe aplastic anemia struggled because of the high cost and limited availability of essential treatments, highlighting the importance of partnerships with higher-income centers for better care.
Malnutrition has a deleterious effect on the results of therapy for malignant diseases in childhood. The impact of radiotherapy on growth is well known but the impact of cytotoxic drugs on nutritional status is more controversial. The purpose of this study was to determine the nutritional status of a cohort of children treated for acute lymphoblastic leukaemia (ALL) in Cuba.
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