Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study.

Context: There are only a few large prospective studies involving evaluation of the effect of maternal thyroid dysfunction on offspring and observations are inconsistent.

Objective: The objective of the study was to investigate the effects of thyroid dysfunction or antibody positivity on perinatal outcome.

Setting And Participants: The study included prospective population-based Northern Finland Birth Cohort 1986 including 9247 singleton pregnancies.

Citalopram and fluoxetine in the treatment of postmenopausal symptoms: a prospective, randomized, 9-month, placebo-controlled, double-blind study.

Objective: Nonhormonal treatment of postmenopausal symptoms is a subject of great interest today. The results of studies on selective serotonin reuptake inhibitors (SSRIs) are promising, but long-term results do not exist. The objective of this study was to evaluate the efficacy of citalopram and fluoxetine in the treatment of physical and psychological menopausal symptoms and their effects on psychosocial and sexual well being in symptomatic postmenopausal women.

Hyperprolactinemia complicating juvenile granulosa cell tumor of the ovary.

Background: Granulosa cell tumors are known to be hormonally active. They usually produce estrogen and inhibin, and the serum inhibin level is often considered a useful tumor marker during the follow-up of this illness.

Case: We present a case of malignant juvenile granulosa cell tumor associated with hyperprolactinemia.