Publications by authors named "E Steen"

Article Synopsis
  • skIMIDs involve immune-mediated diseases that can affect skin and other organs, highlighting the need for interdisciplinary care to improve patient and healthcare practitioner (HCP) experiences.
  • There is a lack of clarity on how patients and HCPs perceive and measure their experiences with this type of care, despite its importance for treatment outcomes and satisfaction levels.
  • A review of 21 studies showed mixed results, with some reporting positive experiences with tailored IC models, while broader geographic studies indicated lower satisfaction levels, emphasizing the need for standardized measurement tools to better understand these experiences.
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Article Synopsis
  • * The study identified TRIM33 as the only bromodomain protein that binds to histone Kla peptides, which suggests that it may help inhibit inflammatory gene expression during macrophage activation.
  • * Using various biophysical techniques, researchers confirmed that TRIM33 has a strong binding affinity for both Kla and acetylated lysine, with a specific glutamic acid residue in its binding pocket crucial for recognizing Kla, highlighting TRIM33's potential role in macrophage polarization and
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. The aim was to demonstrate a reliable method to test the function of the whole heart. .

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Article Synopsis
  • Solitary fibrous tumours (SFTs) and chronic myeloid leukemia (CML) are rare types of tumors that have different genetic changes and symptoms.
  • A male patient in his late 50s, who previously had SFT surgically removed, returned with serious issues like spleen damage and very high white blood cell count, alongside liver tumors.
  • His treatment involved using dasatinib for CML and temozolomide with bevacizumab for SFT, underscoring the importance of considering multiple health conditions and working across disciplines in cancer care.
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Cholelithiasis and its complications are among the most prevalent and costly medical conditions in the United States. Chronic gallbladder disease can progress into more complicated conditions, such as a cholecystoenteric fistula and, more specifically, a cholecystoduodenal fistula (CDF). Repair of these fistulas is complex and usually performed with an open approach.

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