Publications by authors named "E Soto-Perez de Celis"
Pseudomonas aeruginosa is an emergent threat due to the antimicrobial resistance crisis. Bacteriophages (phages) are promising agents for phage therapy approaches against P. aeruginosa.
View Article and Find Full Text PDFBackground And Purpose: Endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) with M2 segment occlusion of the middle cerebral artery (MCA) is debatable. This study assessed the efficacy, safety, and functional outcomes of EVT in M2 occlusion patients, examining differences in outcomes based on the dominance of the occluded segment (DomM2 vs. Non-DomM2).
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- Adoptive cell therapy (ACT) with retrovirally transduced T cells and TriVax vaccination shows promise in boosting antitumor immune responses by expanding specific T cell populations.
- Stat5, a transcription factor, is crucial for T cell proliferation and differentiation, and the study investigates engineered CD8 T cells with active STAT5 in combination with TriVax.
- Results demonstrate that CA-STAT5 enhances T cell expansion, functional capabilities, and reduces exhaustion, leading to a stronger antitumor effect in melanoma models by inhibiting the PD-1/PD-L1 pathway.
Background: The increasing availability of neuroimaging tests has led to a rise in the identification of incidental unruptured intracranial aneurysms (UIAs). Their management is under debate, with no consensus on their follow-up strategy, which can cause anxiety in patients. Our aim is to evaluate the impact of diagnosis and imaging follow-up on daily activities and quality of life.
View Article and Find Full Text PDFBackground: Cerebral edema (CED) is associated with poorer outcome in patients with acute ischemic stroke (AIS). The aim of the study was to investigate the factors contributing to greater early CED formation in patients with AIS who underwent endovascular therapy (EVT) and its association with functional outcome.
Methods: We conducted a multicenter cohort study of patients with an anterior circulation AIS undergoing EVT.