Single oral toxicity assessment and phytochemical analysis of the Ficus erecta Thunb. Leaves extract.

Ficus erecta Thunb. is a traditional medicinal plant used to treat various diseases in Asian countries. We recently reported the potential of the ethanol extract of F.

Myoblast-derived exosomes reduce anticancer drug-induced muscle toxicity via an autocrine pathway.

During cancer treatment, cachexia, characterized by muscle loss, often occurs, with one of the contributing factors being muscle toxicity caused by anticancer drugs. It affects approximately 80% of patients with cancer, particularly those with digestive organ malignancies. However, effective treatment for this condition remains elusive.

Neuroprotective effects of Elaeagnus glabra f. oxyphylla extract in amyloid-beta-induced cognitive deficit mice: Involvement of the PKC-delta, MYL2, and FER pathways.

Elaeagnus glabra f. oxyphylla (EGFO), a member of the Elaeagnaceae family, is an evergreen plant distinct from other species in its genus. We previously reported that ethanol extract from EGFO has memory improvement effects in a short-term memory deficit mouse model and anti-inflammatory effects in a microglial cell line.

Advanced Imaging Integration: Multi-Modal Raman Light Sheet Microscopy Combined with Zero-Shot Learning for Denoising and Super-Resolution.

This study presents an advanced integration of Multi-modal Raman Light Sheet Microscopy with zero-shot learning-based computational methods to significantly enhance the resolution and analysis of complex three-dimensional biological structures, such as 3D cell cultures and spheroids. The Multi-modal Raman Light Sheet Microscopy system incorporates Rayleigh scattering, Raman scattering, and fluorescence detection, enabling comprehensive, marker-free imaging of cellular architecture. These diverse modalities offer detailed spatial and molecular insights into cellular organization and interactions, critical for applications in biomedical research, drug discovery, and histological studies.