A comprehensive analysis and comparison of SPI and SPEI for spatiotemporal drought evaluation.

Assessing drought is crucial for effective water resources management and the development of mitigation strategies. Drought indices serve as indispensable tools in this evaluation process, and choosing an appropriate index is vital for accurate drought assessment. The characteristics and classification of drought depend entirely on the chosen index.

Histological assessment of endometrial polyps resected by hysteroscopy.

Objective: This study aimed to analyze the clinical data and pathologic aspects of endometrial polyps (EMPs) excised completely during surgical hysteroscopy and assess the connection between premalignant and malignant EMPs.

Patients And Methods: This retrospective study includes 489 participants who underwent hysteroscopy due to endometrial polyps, and the clinical features and histological findings of the resected polyps analyzed.

Results: Participants with EMPs were divided into six groups according to histologic findings.

Identifying the environmental hotspots of sulfur-free odorant for LPG storage and filling by life cycle approach.

The main objective of this study is to determine the potential environmental impact of storage and filling the liquefied petroleum gas (LPG) with sulfur-containing (ethyl mercaptan) and sulfur-free (Greenodor) odorants by comparative life cycle assessment (LCA). The LCA was carried out within the scope of ISO 14040 and 14044 Standards in a facility that stores and fills LPG and potential environmental impact was calculated for eleven different impact categories. According to the characterization results, it was determined that the overseas transportation process had the highest impact among all impact categories.

Identification of MicroRNAs that control lipid droplet formation and growth in hepatocytes via high-content screening.

Hepatic lipid droplets (LDs) are associated with metabolic syndrome, type 2 diabetes, hepatitis C, and both alcoholic and nonalcoholic fatty liver disease. MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the level of translation. Approximately 1000 different miRNA species are encoded within the human genome, and many are differentially expressed by healthy and diseased liver.

Identification of host factors involved in borna disease virus cell entry through a small interfering RNA functional genetic screen.

Borna disease virus (BDV), the prototypic member of the Bornaviridae family, within the order Mononegavirales, is highly neurotropic and constitutes an important model system for the study of viral persistence in the central nervous system (CNS) and associated disorders. The virus surface glycoprotein (G) has been shown to direct BDV cell entry via receptor-mediated endocytosis, but the mechanisms governing cell tropism and propagation of BDV within the CNS are unknown. We developed a small interfering RNA (siRNA)-based screening to identify cellular genes and pathways that specifically contribute to BDV G-mediated cell entry.