A Donor Registry: Genomic Analyses of Seagrass Meadows Identifies Adaptive Genotypes for Future-Proofing.

Globally, anthropogenic climate change has caused declines of seagrass ecosystems necessitating proactive restoration approaches that would ideally anticipate future climate scenarios, such as marine warming. In eastern Australia, estuaries with meadows of the endangered seagrass s have warmed and acidified over the past decade, and seagrass communities have declined in some estuaries. Securing these valuable habitats will require proactive conservation and restoration efforts that could be augmented with restoration focussed on boosting resilience to future climate.

Getting rapid diagnostic test data into the appropriate hands by leveraging pharmacy staff and a clinical surveillance platform: a case study from a US community hospital.

Objectives: To outline the procedural implementation and optimization of rapid diagnostic test (RDT) results for bloodstream infections (BSIs) and to evaluate the combination of RDTs with real-time antimicrobial stewardship team (AST) support plus clinical surveillance platform (CSP) software on time to appropriate therapy in BSIs at a single health system.

Methods: Blood culture reporting and communication were reported for four time periods: (i) a pre-BCID [BioFire® FilmArray® Blood Culture Identification (BCID) Panel] implementation period that consisted of literature review and blood culture notification procedure revision; (ii) a BCID implementation period that consisted of BCID implementation, real-time results notification via CSP, and creation of a treatment algorithm; (iii) a post-BCID implementation period; and (iv) a BCID2 implementation period. Time to appropriate therapy metrics was reported for the BCID2 time period.

How storage post sampling influences the stability of sebum when used for mass spectrometry metabolomics analysis?

Sebum is a biofluid excreted by sebaceous glands in the skin. In recent years sebum has been shown to contain endogenous metabolites diagnostic of disease, with remarkable results for Parkinson's Disease. Given that sebum sampling is facile and non-invasive, its potential for use in clinical biochemistry diagnostic assays should be explored including the parameters for standard operating procedures around collection, transport, and storage.