Publications by authors named "E Shlush"
Introduction: To compare histopathological findings of placentas of dichorionic diamniotic twin pregnancies of in-vitro fertilization (IVF), conceived after fresh embryo transfer (ET) and frozen-thawed ET.
Methods: This retrospective study compared dichorionic diamniotic twin IVF pregnancies that resulted in livebirths during 2010-2022. The placental findings were classified according to definitions curated by the 2016 Amsterdam Placental Workshop Group Consensus Statement.
Article Synopsis
- The study investigated the reliability of the sperm chromatin dispersion assay in predicting outcomes of assisted reproductive technology, focusing on its correlation with sperm DNA fragmentation levels.
- Elevated sperm DNA fragmentation was linked to reduced fertilization and embryo cleavage rates, but did not significantly impact overall clinical pregnancy, implantation, miscarriage, or live birth rates.
- A specific analysis of the intracytoplasmic sperm injection method indicated poorer reproductive outcomes compared to other methods, highlighting potential limitations of sperm DNA integrity in assisted reproductive contexts.
Objectives: The limited data regarding obstetrical outcomes in multiple pregnancies following both fresh embryo transfer and frozen-thawed embryo transfer (FET), along with the association between multiple pregnancies and increased pregnancy complications compared to singleton pregnancies, highlight the need for research on this topic. Therefore, this study aimed to compare obstetrical and neonatal outcomes of twin pregnancies after fresh embryo transfer versus FET.
Design: This was a retrospective single-center study.
Both fatty bone marrow (FBM) and somatic mutations in hematopoietic stem cells (HSCs), also termed clonal hematopoiesis (CH) accumulate with human aging. However it remains unclear whether FBM can modify the evolution of CH. To address this question, we herein present the interaction between CH and FBM in two preclinical male mouse models: after sub-lethal irradiation or after castration.
View Article and Find Full Text PDFThe conserved Tweety homolog (TTYH) family consists of three paralogs in vertebrates, displaying a ubiquitous expression pattern. Although considered as ion channels for almost two decades, recent structural and functional analyses refuted this role. Intriguingly, while all paralogs shared a dimeric stoichiometry following detergent solubilization, their structures revealed divergence in their relative subunit orientation.
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