Publications by authors named "E Sharapova"
Article Synopsis
- Metastatic colorectal cancer has a low 5-year survival rate of under 15%, with common metastasis sites being the lungs and liver, while skin metastases are rare and often indicate a worse prognosis.
- A case study of a 62-year-old woman revealed skin metastases from rectal cancer developed two years after treatment, confirming these through histological examination, although differing mutations were found between the primary tumor and skin lesions.
- Despite treatment with FOLFOX6 chemotherapy and bevacizumab, the therapy failed, highlighting the need for close monitoring of skin for metastases in rectal cancer patients, as literature suggests median survival after detection is only 8.5 months.
Article Synopsis
- Diagnosing skin diseases in children is complex, and Incontinentia pigmenti (IP) is a rare hereditary condition that can lead to serious complications like squamous cell carcinoma (SCC) in young patients.
- A case study involving a 10-year-old girl with IP highlights the importance of an interdisciplinary approach, with input from multiple specialists including dermatologists, geneticists, and oncologists.
- Genetic evaluations confirmed a mutation in the gene responsible for IP in the family, leading to successful treatment over a 2-year period, while also revealing varied symptoms among affected family members.
Background: Non-pharmacological treatments based on collagen as a dietary supplement are emerging as a new area of interest to support preventive or therapeutic effects in patients with osteoarthritis (OA).
Aim: In a multicenter, prospective, double-blind, placebo-controlled, randomized study, to evaluate the effectiveness and safety of the use of the Artneo complex containing undenatured chicken collagen type II in patients with OA of the knee joints.
Materials And Methods: The study enrolled 212 outpatients from 12 centers in the Russian Federation with knee OA, stages II and III according to the Kellgren-Lawrence classification.
Aim: To evaluate the relationship of hypercholesterolemia (HCE) with clinical, instrumental, and laboratory parameters in osteoarthritis (OA) in a multicenter, cross-sectional study.
Materials And Methods: The study included 183 patients aged 40-75 years, with a confirmed diagnosis of stage I-III OA (ACR) of the knee joints, who signed an informed consent. The mean age was 55.
Background: Knowledge about the distribution of living organisms on Earth is very important for many areas of biological science and understanding of the surrounding world. However, much of the existing distributional data are scattered throughout a multitude of sources, such as taxonomic publications, checklists and natural history collections and often, bringing them together is difficult. A very successful attempt to solve this problem is the GBIF project, which allows a huge number of researchers to publish data in one place in a single standard.
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