Angiogenic Potential of Multipotent Stromal Cells from the Umbilical Cord: an In Vitro Study.

The mechanisms of proangiogenic activity of multipotent stromal cells from human umbilical cord were analyzed in vitro. The absence of secreted forms of proangiogenic growth factor VEGF-A in the culture medium conditioned by umbilical cord-derived multipotent stromal cells was shown by ELISA. However, the possibility of paracrine stimulation of cell proliferation, mobility, and directed migration of endothelial EA.

Effect of Endothelial Cells on Angiogenic Properties of Multipotent Stromal Cells from the Umbilical Cord during Angiogenesis Modeling in the Basement Membrane Matrix.

Short-term cell culturing on basement membrane matrix is a common and very convenient in vitro model of angiogenesis. We studied the possibility of interaction of multipotent stromal cells from the umbilical cord and Ea.hy926 endothelial cells on this model at the early and late periods of the experiment.

[Lysozyme of hydrobionts and its role in self-purification of water reservoirs].

Model experiments were carried out to study the effects of hydrobiont lysozyme on self-purifying processes of water reservoirs through its participation in the formation of a community of destructive microorganisms. Lysozyme-resistant forms have been found to lie at basis of bacterial cenosis of the Urals, among which there are lysozyme-active and anti-lysozyme-active ones, their population shows an inverse relationship. The exogenous lysozyme that enters the water reservoir in the period when there is a change in the dominant forms of hydrobionts affects the composition of bacterial cenosis by preserving anti-lysozyme-activity with a high activity (6-8 (g/ml), which causes a change in the microbial community of water reservoir, thus affecting the processes of its self-purification.

[Effect of thermal power stations on the sanitary and biological conditions of water reservoirs].

Discharge of thermal waters from power stations can result in the development of thermophilic microorganisms in the water reservoirs and increased water pollution. Increased water temperature changes relationships between lysozyme-active and antilysozyme-active bacteria. The quality of water gets worse.