Publications by authors named "E Seem"

Objectives: Few data exist on mortality among patients with univentricular heart (UVH) before surgery. Our aim was to explore the results of intention to perform surgery by estimating preoperative vs postoperative survival in different UVH subgroups.

Design: Retrospective.

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Article Synopsis
  • The study aimed to assess how effective ixekizumab is for patients with radiographic axial spa (r-axSpA) after 16 weeks, comparing those with different levels of inflammation as indicated by serum CRP and MRI results.
  • Participants included biologic-naïve individuals and those previously treated with TNF inhibitors, receiving either ixekizumab or a placebo; outcomes were measured using the ASAS40 response rate at week 16.
  • Results showed that ixekizumab significantly improved ASAS40 response rates compared to placebo across various inflammation levels, indicating it is effective for treating both high and low inflammation cases of r-axSpA.
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Objectives: Despite Fontan surgery showing improved results, fluid accumulation and oedema formation with pleural effusion are major challenges. Transcapillary fluid balance is dependent on hydrostatic and colloid osmotic pressure (COP) gradients; however, the COP values are not known for Fontan patients. The aim of this study was to evaluate the COP of plasma (COPp) and interstitial fluid (COPi) in children undergoing bidirectional cavopulmonary connection and total cavopulmonary connection.

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Objectives: Following paediatric cardiac surgery with cardiopulmonary bypass (CPB), there is a tendency for fluid accumulation. The colloid osmotic pressure of plasma (COPp) and interstitial fluid (COPi) are determinants of transcapillary fluid exchange but only COPp has been measured in sick children. The aim of this study was to assess the net colloid osmotic pressure gradient in children undergoing atrial septal defect closure.

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